Of course, if you have an issue that is very important to you that could be a deal-breaker (like company culture), you can mention it. Just be prepared for them to take one extreme or the other. For example, maybe you only want to work for companies that buy from vendors in your home country. The hiring manager will let you know if their company does this. And if they don’t, I guess the interview is over.
You describe in the job listing that you are looking for a special education assistant teacher with an abundance of patience and compassion. Having served as a tutor at a summer school for dyslexic children for the past two years, I have developed my ability to be extremely patient while still achieving academic gains with my students. My experience teaching phonics to children aged 6 to 18 has taught me strategies for working with children of all ages and abilities, always with a smile.
Example: “I have a passion for application development that’s grown stronger over the course of my career. The company’s mission aligns with my personal values and, from my limited time in the office, I can already tell this is the sort of positive culture in which I would thrive. I want to work for a company that has the potential to reshape the industry, and I believe you’re doing just that.”
Tip: It’s easy to get hung up on figuring out your single most impressive accomplishment. Instead, think of a few achievements that showcase your work ethic and values. If you can, pick examples that also tie back to the job you’re applying for. The STAR method is a great tool to ensure you highlight not only your role but how you drove business results.
Answers to this question go one of two basic ways. Candidates try to show their incredible ambition (because that's what they think you want) by providing an extremely optimistic answer: "I want your job!" Or they try to show their humility (because that's what they think you want) by providing a meek, self-deprecating answer: "There are so many talented people here. I just want to do a great job and see where my talents take me."